Acyclovir eye ointment pdf

However, if it is nearly time for your next application, skip the missed application. Wash your hands with soap and water before and after using this medication. Other preparations of this medicine may still be available. Zovirax ointment 5% is a formulation for topical administration. Clean and dry the affected areas before applying the medication. Zovirax ophthalmic ointment does not get rid of the virus from your body. Ointments and creams used in the pharmaceutical and cosmetics industry may contain solid particles andor emulsion droplets. Acyclovir topical ointment 5pct drug medication dosage. Acyclovir is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity interferes with viral replication against the herpes viruses, including herpes simplex 1 and 2. Do not touch the tip of the bottle to your childs eye or anything else. Acyclovir ointment, usp is a synthetic nucleoside analogue active against herpes viruses. If you forget to use aciclovir if you forget to use aciclovir, use it as soon as you remember.

Formulation and evaluation of acyclovir ophthalmic inserts article pdf available in asian journal of pharmaceutical sciences 32. Zovirax eye ointment contains aciclovir 3% ww as the active ingredient. Manual searching included index medicus from 1960 through 1965 and. Acyclovir topical ointment 5pct drug medication dosage information. Read all of this leaflet carefully before you start using this medicine because it contains important information for you. Application for the inclusion of aciclovir eye ointment in the who list. Zovirax ophthalmic ointment acyclovir drug medicine. Acyclovir ointment usp, 5% is contraindicated in patients who develop hypersensitivity to the components of the formulation. Acyclovir ointment usp, 5% is a formulation for topical administration. Read all of this leaflet carefully before you start using this. Pdf on apr 14, 2012, milind baburao ubale and others published a validated stabilityindicating hplc assay method for acyclovir in bulk drug. Try to avoid the tip of the tube touching any part of your eye. Aciclovir eye ointment for herpes simplex infection this leaflet is about the use of aciclovir eye ointment for the treatment of infections caused by the varicella zoster virus or. Acyclovir acyclovir sodium dose, indications, adverse.

Do not use zovirax ophthalmic ointment if the packaging is torn or shows signs of tampering. Aciclovir eye ointment for herpes simplex infection. Zovirax ophthalmic ointment is contraindicated in patients with a known hypersensitivity to aciclovir or valaciclovir, or any of the excipients listed in section 6. Capitals indicate lifethreatening, underlines indicate most frequent. Do not touch the tip of the bottle to your eye or anything else.

Use this ointment as soon as possible after you notice the beginning of a herpes sore pain, burning, blisters, or itching. Aciclovir eye ointment is for use in the eye, if you swallow any talk to your doctor or pharmacist. The recommended dosing regimen is to apply a 1 cm ribbon of ointment in the lower culdesac of the affected eye 5 times per day approximately every 3 hours while awake until the corneal ulcer heals and then a 1 cm ribbon 3 times per day for 7 days. Begin using acyclovir as soon as symptoms of a herpes infection appear. While effective, they tended to have low bioavailability and measurable local cellular toxicity due to their nonselective mode of action. Zovirax ointment uses include the treatment of genital herpes and cold sores. Consumer information about the medication acyclovir ointment topical zovirax, includes side effects, drug interactions, recommended dosages, and storage information. To assess whether antiviral treatment can prevent recurrences of ocular hsv disease, we conducted a. Apply 1cm about 12 an inch of zovirax eye ointment to the inside of your lower eyelid. A vast amount of practicerelated information is available to todays healthcare practitioner. Aciclovir eye ointment for herpes simplex infection medicines for.

Acyclovir ophthalmic ointment avaclyr 3% treatment of acute herpetic keratitis dendritic ulcers apply 1 cm of ointment in the lower culdesac of the affected eye 5 times per day until. Each gram of zovirax ointment 5% contains 50 mg of acyclovir in a polyethylene glycol peg base. Do not use zovirax ophthalmic ointment if the expiry date exp printed on the pack has passed. Zovirax ophthalmic ointment is only suitable for use in the eye. Reconstitute 500mg or 1g vial with 10 ml or 20 ml, respectively, of sterile water for injection. Pdr drug summaries are concise pointofcare prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice pdr s drug. If this happens, wash right away with plenty of water. Ophthalmic ointment contains 30 mg of aciclovir in white soft paraffin base aciclovir 3 per cent. Zovirax ophthalmic eye ointment acyclovir consumer medicine information name address what is in this leaflet this leaflet answers some common questions about zovirax ophthalmic. Precautions and warnings with acyclovir ointment to be aware of prior to taking it include the fact that it is not intended to be used to treat herpes infections of the eye. This information has been left on emc for reference purposes. What zovirax eye ointment is and what it is used for zovirax eye ointment contains a medicine called aciclovir. With the other hand, put a small ribbon of ointment into the pouch.

The pharmaceutical company has decided to discontinue this product. Zovirax is the brand name for acyclovir, a synthetic nucleoside analogue active against herpes viruses. Patients should avoid wearing contact lenses when using zovirax ophthalmic ointment. Fiftyseven patients with hzo within 72 hours of the onset of rash received either topical acyclovir ointment or 800 mg oral acyclovir, both 5 times daily for 7 days, and were. Aciclovir eye ointment for herpes simplex infection this leaflet is about the use of aciclovir eye ointment for the treatment of infections caused by the varicella zoster virus or herpes simplex virus. Avaclyr is used to treat acute herpetic keratitis dendritic ulcers in the eye in patients with herpes simplex hsv1 and hsv2 virus. Acyclovir ointment 5% is a formulation for topical administration. Pdf formulation and evaluation of acyclovir ophthalmic. Pdf a validated stabilityindicating hplc assay method. Herpes simplex virus hsv is an important cause of corneal disease and visual loss. Your doctor may have prescribed zovirax ophthalmic ointment. Resistant strains have been isolated in vitroand in animals following treatment with aciclovir.

Zovirax ophthalmic ointment works by stopping the production of the herpes simplex virus. Aciclovir the active ingredient in zovirax ophthalmic ointment belongs to a group of. While the drug is not a cure for these conditions, it can help symptoms heal faster by preventing the herpes. Acyclovir is a synthetic nucleoside analogue active against herpes viruses. Nda 202408 page 4 prescribing information for avaclyr. During the toxicosis induced by thelarger doses of acyclovir, plasma levels of the drug. Twenty nine published clinical trials with acyclovir acv ophthalmic. Generic drugs usually cost less than the brandname version. Acyclovir should not be used more frequently or longer than prescribed. Wash your hands after applying zovirax eye ointment. Avaclyr is a topical sterile ointment containing 3% acyclovir. Take missed doses as soon as possible but not just before next dose is due.

Patientfamilyteaching instruct patient to take medication as directed for the full course of therapy. Acyclovir read all of this leaflet carefully before you start using. Zovirax eye ointment patient information leaflet pil. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. Acyclovir oral tablet is a prescription drug thats available as the brandname drug zovirax. Do not administer acyclovir injectable topically, im, subcut, po, or in the eye.